There is an uprising of baboons which led to the death of the President as Axe Cop enlists the Almighty Bear and his bear army of Bearopolis to help fight the baboon army. When the baboon army plans to target the Secret President, Axe Cop, Flute Cop, and the Almighty Bear must enter the Secret President's bloodstream in order to confront the baboon's leader the Almighty Baboon.